Leo Betschart

Postdoctoral Fellow

• •  2017-present Postdoctoral Fellow, Swiss National Science Foundation Award “Early Postdoc.Mobility”
  •  2011–2016 PhD, ETH Zürich, Switzerland, Advisor: Prof. Dr. K.-H. Altmann
  • 2010 Trainee, Novartis Institute of Biomedical Research (NIBR), Basel, Switzerland
  • 2009–2010 Master’s Thesis, The Scripps Research Institute, USA, Advisors: Prof. Dr. K. C. Nicolaou and Prof. Dr. E. M. Carreira
  • 2005–2010 M.Sc. (Chemistry), ETH Zürich, Advisors: Prof. Dr. E. M. Carreira and Prof. Dr. A. Togni

Consult my linkedin profile for a more detailed account.

Phone: 604-822-4626
Email: leob(at)chem.ubc.ca

RESEARCH INTEREST

My current research is at the interface of chemistry and biology: The main part involves the synthesis of carbohydrate-based biological tool compounds. The second part is centered around evaluating the new compounds against enzymes and bacteria. A number of derivatives will be tested for their antibacterial activities. Other sets of compounds will serve as sensitive and selective tool compound for the screening of metagenomic libraries in search of new glycosidases.

PUBLICATIONS

1. Betschart, L.; Altmann K.-H. „Xenicane Natural Products: Biological Activity and Total Synthesis” Current Pharmaceutical Design, 2015, 21, 5467-5488.
2. Zurwerra, D.; Glaus, F.; Betschart, L.; Schuster, J; Gertsch, J.; Ganci, W.; Altmann, K.-H. „Total Synthesis of (−)-Zampanolide and Structure–Activity Relationship Studies on (−)-Dactylolide Derivatives” Chemistry – A European Journal, 2012, 18, 16868-16883.